Human platelet lysate is a xeno-free, ready-to-use alternative to fetal bovine serum (FBS). The essential growth-promoting factors of FBS are derived from activated bovine platelets. Human platelet lysate is derived from human platelets and contains all essential nutrients and growth factors from platelet lysis. It shows comparable to improved cell growth in adherent and non-adherent primary cells (including primary mesenchymal stem cells) and is successfully used as an additive in human and animal in vitro cell culture as well as for in vivo wound healing and tissue reconstruction.
Xeno-free - Without animal ingredients Sustainable - Promotes animal welfare Rich in growth factors and cytokines - Comparable/improved cell growth to FBS High reproducibility - No batch variations High safety - From certified EU donor institutes
Good to know
Our human platelet lysate is made from human platelet concentrates produced by certified EU donor institutes. As platelet concentrates for transfusions must not be older than 5 days, 5-20% of the collected platelet concentrates are not used. These platelet concentrates are pooled, lysed by freezing and thawing processes and cell debris is removed by centrifugation.
Our human platelet lysate contains potent growth factors and cytokines, important nutrients such as vitamins, minerals, electrolytes and proteins. Since platelets are stored in plasma, Human Platelet Lysate usually also contains plasma proteins and carriers such as fibrinogen. Our Human Platelet Lysate is defibrinated. No additional enzymes such as thrombin are required. Furthermore, no addition of heparin is necessary.
Application
in vitro cultivation of adherent/not adherent primary cells