G418

G418 (geniticin) is an aminoglycoside antibiotic that has a toxic effect on prokayrotic and eukaryotic cells. It blocks protein synthesis by disrupting ribosomal function. In eukaryotic cell culture, G418 serves as a selection antibiotic for transformed cells that have been stably transfected with neomycin resistance genes.

Article list - Solutions

Products	Article number	Quantity	Shop
G418 (50 mg/ml G418 disulfate in water)	BS.A2912	100 ml
G418 (100 mg/ml G418 disulfate in water)	BS.A2913	100 ml

Article list - Powder

Products	Article number	Quantity
G418 Disulfate Dry matter	BS.A291-21	1 g
	BS.A291-23	5 g
	BS.A291-25	10 g

Product information

Category:	Antibiotic
Product type:	G418
Sterilization:	Sterile filtered
Form:	Liquid + Powder

Application

Selection antibiotic for transformed cells containing neomycin resistance genes

Publications

Meso-Scale Modifications in Additively Manufactured Zirconia: Topographical Design and Its Influence on Cell–Material Interactions

Sebastian Hetzler, Stefan Rues, Andreas Zenthöfer, Peter Rammelsberg, Reinald Kühle, Christopher J. Lux, Ralf Erber, Christoph J. Roser

Bioengineering (2026) 13, 498