FBS High Performance
FBS High Performance is a specially developed FBS with a significantly reduced serum content. For our product, natural FBS (20%) was mixed with identified growth factors in a synthetic, highly concentrated form. Through an additional chromatographic removal of endotoxins (lipopolysaccharides), FBS High Performance represents an almost defined serum with minimised batch fluctuations. FBS High Performance offers a more sustainable alternative to natural FBS and shows consistent or even improved cell cultivation properties. The reduced serum content also promotes animal welfare.
Properties
Semi-synthetic - Defined quality
Reduced serum content - Sustainable/Promotes animal welfare
Defined composition - Minimal batch variations/Consistent quality
High safety - Virus/Mycoplasma tested
Good to know
In order to create in vivo conditions for in vitro cell culture, serum is usually added to the cell culture medium. Serum serves the cells as a source of growth factors, lipids, hormones and minerals. Fetal bovine serum (FBS) is particularly rich in growth factors and contains few antibodies that could interfere with cell cultivation. This unique composition makes FBS one of the most important supplements for cell proliferation in in-vitro cell culture.
However, the increasing demand for FBS is met with limited availability and leads to significant animal welfare concerns. Many scientists are therefore trying to find serum-free substitutes. So far, however, it has not been possible to produce a suitable synthetic substitute with comparable growth-promoting properties.
FBS High Performance contains 20% natural FBS and is mixed with key components for optimum cell growth in a highly concentrated, synthetic form. Our product is therefore virtually defined and has minimal batch to batch variation. FBS High Performance shows comparable or even improved cell growth and morphology and reduced cell stress in cell culture. Due to the reduced serum content, this product also promotes animal welfare.
Add FBS High Performance to your cell culture medium at the same concentration as your standard FBS. Heat inactivation of the product is not recommended.
FAQs
What certifications do I need for routine research with fetal calf serum?
✔ CoA (Certificate of Analysis)
✔ CoO (Certificate of Origin)
✔ Virus-Tests
✔ BSE/TSE statement - optional
All of the above certificates are available on request:
Product information
Category: | Fetal bovine serum (FBS) |
Origin: | USA/ South America |
Species of origin: | Beef |
Sterilisation: | Sterile filtered |
Liquid/Powder: | Liquid |
Application
- Cultivation of adherent and suspension cells
- Production and expansion of stem cells
- Cultivation of viruses
- Cell-based vaccine production
Publications
Immunoglobulin heavy-chain status and stromal interactions shape ferroptosis sensitivity in chronic lymphocytic leukemia
Martin Böttcher, Lea Reemts, Paul J. Hengeveld, Romy Böttcher-Loschinski, Vikas Bhuria, Junyan Lu,
Silvia Materna-Reichelt, Durdam Das, Natasa Stojanović Gužvić, Heiko Bruns, Wolfgang Huber, Thorsten Zenz,
Denny Schanze, Martin Zenker, Sascha Dietrich, Anton W. Langerak and Dimitrios Mougiakakos
Springer Nature: Signal Transduction and Targeted Therapy (2026) 11:3