Specially treated FBS
Fetal bovine serum (FBS) is one of the most important supplements in cell culture. However, standard FBS is not always sufficient for certain cell lines and experimental applications. Individual components of the serum can influence analyses, or specific requirements regarding purity and composition may necessitate additional treatment of the serum. That is why we offer a comprehensive range of specially treated FBS for cell culture:
Specialized Fetal Bovine Serum for Specific Requirements
Bio&SELL offers a comprehensive range of specially treated FBS for cell culture. This includes:
FBS Low Endotoxin - With reduced endotoxin content
FBS Low IgG - With reduced IgG content
FBS Heat-inactivated - Heat-inactivated for 30 minutes at 56°C
FBS Tetracycline-negative - FBS free of tetracyclines
FBS Exosome-depleted - FBS free of exosomes
FBS Delipidated - Delipidated FBS for studies on atherosclerosis and lipid metabolism
FBS Dialyzed - FBS with reduced concentration of low-molecular-weight compounds (cut-off = 10 kDa)
FBS Activated Charcoal - FBS with reduced levels of steroid hormones, cytokines, and viruses
FBS Gamma-Irradiated - FBS sterilized with gamma rays
Select the appropriate fetal bovine serum for your cell line and application.
The right specially treated FBS for your application
The choice of the appropriate fetal bovine serum depends largely on the cell line used, the experimental setup, and the scientific question being addressed. For example, while low-endotoxin FBS is suitable for cell cultures that are particularly sensitive to endotoxins, exosome-depleted FBS is ideal for exosome research, and dialyzed FBS is recommended for experiments where low-molecular-weight serum components need to be reduced.
With a variety of specially treated FBS products, Bio&SELL offers the ability to tailor the cell culture serum used to specific experimental requirements.
Discover Bio&SELL’s range of specially treated FBS and find the right fetal bovine serum for your cell culture and research application.
FAQs
What is specially treated FBS?
Specially treated FBS (fetal bovine serum) is fetal bovine serum that has been specifically adapted for certain scientific applications through additional processing steps. Depending on the treatment, for example, endotoxins, immunoglobulins, lipids, low-molecular-weight components, or exosomes can be reduced, or certain biological properties can be modified. Bio&SELL offers various specially treated FBS variants for demanding cell culture and research applications.
What types of specially treated FBS are available from Bio&SELL?
Bio&SELL offers various specialty FBS products, including FBS Low Endotoxin, FBS Low IgG, Heat-Inactivated FBS, Tetracycline-Negative FBS, Exosome-Depleted FBS, Delipidated FBS, Dialyzed FBS, Activated Carbon/Dextran FBS, and Gamma-Irradiated FBS. The variants differ in terms of their treatment and intended applications.
What is FBS Low Endotoxin?
Low Endotoxin FBS is a specially treated fetal bovine serum with an exceptionally low endotoxin content. Bio&SELL offers variants with endotoxin levels of < 1 EU/ml (Ultra Low Endotoxin), < 5 EU/ml (Very Low Endotoxin), and < 10 EU/ml (Low Endotoxin). The serum is suitable for, among other applications, sensitive cell lines, primary cell cultures, hybridoma cloning, and transfection.
Low Endotoxin FBS is particularly useful when endotoxins could affect the cell culture or the course of the experiment. This includes, for example, sensitive cell cultures and transfection experiments. A reduced endotoxin content can help improve the reproducibility of experiments.
How do I find the right specially treated FBS?
The choice of the appropriate FBS depends on the specific cell line, the experimental setup, and the interfering serum components. Low-endotoxin FBS, for example, is suitable for applications with high sensitivity to endotoxins, while dialyzed FBS may be useful for studies involving defined low-molecular-weight components. For hormone-dependent studies, for example, delipidized or activated carbon/dextran-treated FBS may be suitable.
Can I receive an FBS sample before purchasing?
Yes. Bio&SELL offers the option to request a sample for various FBS products. This is particularly useful for FBS, as the suitability of a serum can depend on the specific cell line and the individual experimental setup.



